Cancer cells rely on high levels of ER stress response to deal with misfolded proteins and rapid growth. Excessive and prolonged UPR activation has been… Read More »Endoplasmic reticulum stress and cancer therapy
Brandizzi, F. & Barlowe, C. Organization of the ER–Golgi interface for membrane traffic control. Nat. Rev. Mol. Cell Biol. 14, 382–392 (2013). Kohno, K., Normington,… Read More »What causes endoplasmic reticulum stress
Abstract Different physiological and pathological conditions can perturb protein folding in the endoplasmic reticulum, leading to a condition known as ER stress. ER stress activates… Read More »Linking er stress to autophagy potential implications for cancer therapy
Please take note that unboxing videos are required for multi-part equipment like skimmer, canister filter, LED lights, and pumps in order to verify that the… Read More »How to use stress heal in aquarium
Figure 1.Endoplasmic Reticulum (ER) homeostasis/stress and the unfolded protein response (UPR) signaling in physiopathologic conditions. The UPR consists of three signaling pathways initiated by detachment… Read More »The role of endoplasmic reticulum stress in human pathology
The goals of dietary therapy are to optimize body weight with appropriate protein and carbohydrate levels, fat restriction, and calorie and portion control. Weight loss… Read More »What are the objectives of diet therapy
The goals of dietary therapy are to optimize body weight with appropriate protein and carbohydrate levels, fat restriction, and calorie and portion control. Weight loss… Read More »Explain the objectives of diet therapy
Cellular stress response The integrated stress response is a cellular stress response conserved in eukaryotic cells that downregulates protein synthesis and upregulates specific genes in… Read More »What is the integrated stress response
